Tag: brain scan

The Latest in Brain Imaging News

In recent years, awareness surrounding brain injuries has steadily risen, prompting significant strides in diagnostic technologies and treatment modalities. As we delve into the latest developments in this critical area of healthcare, it becomes increasingly apparent that advancements in medical imaging, particularly in the realm of neurological disorders, are poised to revolutionize the landscape of brain injury diagnosis and management.

 

AI-based Quantitative Brain Imaging System

Philips and Synthetic MR have joined forces to advance the diagnosis of neurological disorders through cutting-edge quantitative brain imaging tools. Their collaboration introduces the Smart Quant Neuro 3D MRI software suite, combining Philips’ SmartSpeed image-reconstruction technology, the 3D SyntAc clinical application, and SyntheticMR’s SyMRI NEURO 3D software. This innovation employs AI to analyze brain tissues, enhancing the detection and analysis of conditions like multiple sclerosis, traumatic brain injuries, and dementia.

The rise of AI in diagnostic imaging, projected to reach $1.2bn by 2027, signifies a transformative shift in improving accuracy and patient outcomes. With the diagnostic imaging market expected to grow to $9.1bn by 2030, fueled by demand for early disease diagnosis and personalized medicine, this partnership underscores the crucial role of AI in enhancing medical imaging.

Read the press release here.

 

A New Way of Diagnosing Mild TBIs

Researchers have developed a novel brain imaging method to diagnose mild traumatic brain injuries (mTBIs), which are often missed by standard techniques like MRI. This method involves loading gadolinium, a common MRI contrast agent, into micropatches attached to immune cells called macrophages. These cells migrate to areas of brain inflammation caused by mTBIs, enabling MRI detection. The technique, called M-GLAMs, was successfully tested in mice and pigs, showing promise for accurately diagnosing mTBIs. It also allows imaging at lower gadolinium doses, potentially benefiting patients with kidney issues. While unable to pinpoint injury locations, M-GLAMs could aid in identifying and treating brain inflammation. The researchers aim to bring this technology to clinical trials, with support from grants and intellectual property protection.

Read the study here.

tbi

New Imaging Tech that Captures Neuronal Activity Across the Brain During Recovery

Researchers at Tufts University School of Medicine have developed a novel imaging technology to monitor neuronal activity throughout the entire brain during the initial weeks of recovery from traumatic brain injury (TBI). Their study, published in Cerebral Cortex, reveals that TBI can induce changes in brain function beyond the injury site. Using a combination of fluorescent sensors and electrodes, they observed altered connectivity patterns in mice post-injury, even in regions distant from the impact. Despite the mice’s ability to perform physical tasks normally, their brain activity during both exercise and rest differed significantly from healthy brains. This impaired ability to switch between states suggests underlying brain state dysfunction post-injury. The findings highlight the brain’s plasticity in response to injury and have potential clinical implications for understanding TBI impacts and tailoring treatments. The researchers aim to further investigate long-term neural activity changes post-recovery and explore the technology’s potential in predicting specific dysfunctions or long-term outcomes of TBI. 

Read the study here.

 

 

Sources:

Medicaldevice-network.com
Otd.harvard.edu
Scitechdaily.com
Openai.com

 

A device recently approved by the U.S. FDA made extremely precise images of a postmortem sample

A 100-hour MRI scan captured the most detailed look yet at a whole human brain

https://www.sciencenews.org/article/mri-scan-most-detailed-look-yet-whole-human-brain

A device recently approved by the U.S. FDA made extremely precise images of a postmortem sample .
BY

Over 100 hours of scanning has yielded a 3-D picture of the whole human brain that’s more detailed than ever before. The new view, enabled by a powerful MRI, has the resolution potentially to spot objects that are smaller than 0.1 millimeters wide.

“We haven’t seen an entire brain like this,” says electrical engineer Priti Balchandani of the Icahn School of Medicine at Mount Sinai in New York City, who was not involved in the study. “It’s definitely unprecedented.”

The scan shows brain structures such as the amygdala in vivid detail, a picture that might lead to a deeper understanding of how subtle changes in anatomy could relate to disorders such as post-traumatic stress disorder.

To get this new look, researchers at Massachusetts General Hospital in Boston and elsewhere studied a brain from a 58-year-old woman who died of viral pneumonia. Her donated brain, presumed to be healthy, was preserved and stored for nearly three years.

Before the scan began, researchers built a custom spheroid case of urethane that held the brain still and allowed interfering air bubbles to escape. Sturdily encased, the brain then went into a powerful MRI machine called a 7 Tesla, or 7T, and stayed there for almost five days of scanning.

The strength of the 7T, the length of the scanning time and the fact that the brain was perfectly still led to the high-resolution images, which are described May 31 at bioRxiv.org. Associated videos of the brain, as well as the underlying dataset, are publicly available.

Researchers can’t get the same kind of resolution on brains of living people. For starters, people couldn’t tolerate a 100-hour scan. And even tiny movements, such as those that come from breathing and blood flow, would blur the images.

But pushing the technology further in postmortem samples “gives us an idea of what’s possible,” Balchandani says. The U.S. Food and Drug Administration approved the first 7T scanner for clinical imaging in 2017, and large medical centers are increasingly using them to diagnose and study illnesses.

These detailed brain images could hold clues for researchers trying to pinpoint hard-to-see brain abnormalities involved in disorders such as comas and psychiatric conditions such as depression. The images “have the potential to advance understanding of human brain anatomy in health and disease,” the authors write.